OUR VIEW AND A NEW PERSPECTIVE

Autism spectrum disorder (ASD) is primarily a congenital developmental disability

characterized with impaired social interaction and language skills and

restricted/repetitive behavior in the toddler period and later in life.

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Causes: ASD is caused by a maternal-to-fetal infection and inflammation resulting in

aberrant immune activation, formation of latent reactivatable infections, proinflammatory

microbiome, and disruption of central nervous system. Under “pressure” of continuous

inflammation and infections, these pathologic changes in a child start in the prenatal

period, continue throughout the postnatal period disrupting gene regulation, causing

atypical brain development, changes in other organs, and eventually establishing the

autistic phenotype.

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Treatments for ASD should be etiopathogenetic. It includes antiviral, antibacterial, anti-

inflammatory, antioxidant, immunomodulatory, microbiome-correcting and

neuroprotective therapies. All these treatments for ASD should start as soon as possible

after the diagnosis is confirmed. Initially, it should include medication (non-injectable)

therapy and continues as maintenance with scientifically proven supplements.