Nystatin is an antifungal medication that acts locally within the gastrointestinal tract and oral cavity to treat infections caused by susceptible Candida species. Because it is minimally absorbed into the bloodstream, Nystatin works directly where fungal overgrowth occurs while producing very limited systemic exposure.

Nystatin works by binding to ergosterol, an essential component of the fungal cell membrane, disrupting its integrity and leading to the elimination of susceptible yeast organisms.

Nystatin is commonly used in physician-directed treatment programs involving intestinal Candida overgrowth, oral thrush, and fungal dysbiosis, particularly during or following prolonged antibiotic therapy. In integrative protocols, it is frequently incorporated into comprehensive gut health strategies for selected patients.

Dosage, duration of therapy, and monitoring requirements should always be determined by a qualified healthcare professional based on the patient's age, weight, medical history, and treatment goals.