PQQ (Pyrroloquinoline Quinone) and Alpha-Lipoic Acid (ALA) are commonly combined to support mitochondrial function, cellular energy production, antioxidant protection, and neurological health. Together they help protect cells from oxidative stress while promoting healthy mitochondrial activity.

This combination is frequently used in integrative medicine to support brain function, nerve health, energy metabolism, and recovery from chronic inflammation and oxidative stress.

Potential Benefits

• Supports mitochondrial function and biogenesis
• Promotes healthy cellular energy production
• Provides antioxidant protection
• Supports nerve health and regeneration
• Helps reduce oxidative stress
• Supports cognitive function and mental clarity
• Promotes healthy aging and cellular resilience
• Supports metabolic health
• Helps maintain healthy neurological function

How It Works

• PQQ supports the formation of new mitochondria (mitochondrial biogenesis)
• PQQ helps protect mitochondria from oxidative damage
• Alpha-Lipoic Acid supports mitochondrial energy production
• ALA helps regenerate antioxidants such as glutathione, vitamin C, and vitamin E
• Together they support cellular repair, energy metabolism, and neurological function

Why It Is Helpful in AN Protocol

For autistic children and adults, as well as individuals with PANS/PANDAS and neuroimmune disorders:

• Supports mitochondrial dysfunction commonly associated with chronic inflammation
• Helps maintain healthy brain energy metabolism
• Supports nerve repair and neurological function
• May improve mental clarity and cognitive performance
• Helps reduce oxidative stress affecting the nervous system
• Supports overall cellular resilience and recovery

Key Mechanism

PQQ + ALA supports health primarily through:

• Mitochondrial biogenesis
• Cellular energy production
• Antioxidant protection
• Nerve support
• Reduction of oxidative stress

Suggested Use

Typical formulation:

• PQQ 10–20 mg daily
• Alpha-Lipoic Acid 200–300 mg daily

or as directed by a healthcare professional.

Classification

Primary Category

• Neuropathy and Nerve Growth

Secondary Categories

• Mitochondrial and Metabolic Support
• Brain and Cognitive Support
• Anti-Inflammatory and Antioxidant Support
• Healthy Aging Support