Magnesium 400 mg
Nervous System, Muscle, and Neuroimmune Support

Description & Directions

Magnesium is an essential mineral involved in more than 300 enzymatic reactions throughout the body. It plays a critical role in nervous system function, muscle relaxation, energy production, cardiovascular health, and immune regulation.

Magnesium deficiency is common and may contribute to anxiety, irritability, sleep disturbances, muscle tension, headaches, constipation, fatigue, and impaired stress tolerance.

Magnesium supplementation is widely used in integrative medicine to support neurological function, relaxation, healthy sleep, and inflammatory balance.

Potential Benefits
Supports healthy nervous system function
Promotes relaxation and calmness
Supports healthy sleep quality
Helps reduce muscle tension and cramps
Supports energy production and mitochondrial function
Promotes cardiovascular health
Supports healthy glucose metabolism
Helps maintain normal bowel function
Supports immune regulation
May reduce neuroinflammation and oxidative stress
Mechanism of Action

Magnesium participates in:

ATP (cellular energy) production
Neurotransmitter regulation
Muscle contraction and relaxation
Calcium balance
DNA and protein synthesis
Nerve signal transmission
Regulation of inflammatory pathways

Magnesium also acts as a natural modulator of NMDA receptors, helping maintain healthy excitatory neurotransmission and nervous system balance.

Potential Role in Neuroimmune and Autism-Related Protocols

In Dr. Ken Alibek's integrative approach, magnesium may be considered when there is evidence of:

Autism Spectrum Disorder (ASD)
PANS/PANDAS
Anxiety and OCD symptoms
Hyperactivity and irritability
Sleep disturbances
Constipation
Chronic inflammation
Neuroinflammation
Mitochondrial dysfunction
Chronic stress

Many children and adults with autism, PANS/PANDAS, or chronic inflammatory conditions may benefit from magnesium support as part of a broader physician-supervised treatment program.

Forms of Magnesium

Magnesium Glycinate

Excellent absorption
Often preferred for anxiety, sleep, and nervous system support

Magnesium Citrate

Good absorption
May help with constipation

Magnesium Malate

Supports energy production and muscle function

Magnesium Threonate

Crosses the blood-brain barrier efficiently
Often used for cognitive and neurological support

Magnesium Oxide

Lower absorption
Commonly used for constipation
Suggested Use

Typical adult dosing:

400 mg daily
May be taken once daily or divided into two doses
Often taken in the evening for relaxation and sleep support
Possible Side Effects

Most common:

Loose stools
Diarrhea (especially magnesium citrate or oxide)
Mild abdominal discomfort

Less common:

Nausea
Fatigue if excessive doses are used
Precautions
Individuals with kidney disease should consult their healthcare provider before use.
Excessive magnesium intake may cause diarrhea and electrolyte imbalance.
Magnesium may interfere with the absorption of certain medications and should generally be taken at least 2 hours apart from antibiotics, thyroid medications, and some mineral supplements.
Important Note

Magnesium is a dietary supplement, not a medication. It is commonly used to support nervous system function, relaxation, sleep quality, muscle health, and immune balance. In children and adults with Autism Spectrum Disorder (ASD), PANS/PANDAS, ADHD, anxiety, OCD, chronic infections, neuroinflammation, constipation, or mitochondrial dysfunction, magnesium may be considered as part of a broader physician-supervised integrative treatment program. The choice of magnesium form should be individualized based on the patient's symptoms and therapeutic goals.